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Trends in the Use, Sociodemographic Correlates, and Undertreatment of Prescription Medications for Chronic Obstructive Pulmonary Disease among Adults with Chronic Obstructive Pulmonary Disease in the United States from 1999 to 2010
PLOS One
  • Earl S. Ford, Centers for Disease Control and Prevention
  • David M. Mannino, University of Kentucky
  • Anne G. Wheaton, Centers for Disease Control and Prevention
  • Letitia Presley-Cantrell, Centers for Disease Control and Prevention
  • Yong Liu, Centers for Disease Control and Prevention
  • Wayne H. Giles, Centers for Disease Control and Prevention
  • Janet B. Croft, Centers for Disease Control and Prevention
Abstract

BACKGROUND: The extent to which patients with COPD are receiving indicated treatment with medications to improve lung function and recent trends in the use of these medications is not well documented in the United States. The objective of this study was to examine trends in prescription medications for COPD among adults in the United States from 1999 to 2010.

METHODS: We performed a trend analysis using data from up to 1426 participants aged ≥20 years with self-reported COPD from six national surveys (National Health and Nutrition Examination Survey 1999-2010).

RESULTS: During 2009-2010, the age-adjusted percentage of participants who used any kind of medication was 44.2%. Also during 2009-2010, the most commonly used medications were short-acting agents (36.0%), inhaled corticosteroids (ICS) (18.3%), and LABAs (16.7%). The use of long-acting beta-2 agonists (LABAs) (p for trend

CONCLUSION: The percentages of adults with COPD who reported having various classes of prescription medications that improve airflow limitations changed markedly from 1999-2000 to 2009-2010. However, many adults with COPD did not report having recommended prescription medications.

Document Type
Article
Publication Date
4-21-2014
Notes/Citation Information

Published in PLOS One, v. 9, issue. 4, e95305.

This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

Digital Object Identifier (DOI)
http://dx.doi.org/10.1371/journal.pone.0095305
Citation Information
Earl S. Ford, David M. Mannino, Anne G. Wheaton, Letitia Presley-Cantrell, et al.. "Trends in the Use, Sociodemographic Correlates, and Undertreatment of Prescription Medications for Chronic Obstructive Pulmonary Disease among Adults with Chronic Obstructive Pulmonary Disease in the United States from 1999 to 2010" PLOS One Vol. 9 Iss. 4 (2014) p. 95305 - 95305
Available at: http://works.bepress.com/david_mannino/268/