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Article
MMP-13 Selective Isonipecotamide Alpha-sulfone Hydroxamates
Bioorganic & Medicinal Chemistry Letters
  • Stephen A. Kolodziej
  • Susan L. Hockerman
  • Gary A. DeCrescenzo
  • Joseph J. McDonald
  • Grace E. Munie
  • Theresa R. Fletcher
  • Nathan Stehle
  • Craig Swearingen
  • Daniel Becker, Loyola University Chicago
Document Type
Article
Publication Date
6-15-2010
Pages
3561-3564
Publisher Name
Elsevier
Disciplines
Abstract

A series of N-aryl isonipecotamide α-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP-13.

Comments

Author Posting © Elsevier, 2010. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Bioorganic & Medicinal Chemistry Letters , Volume 20, Issue 12, June 15, 2010. http://dx.doi.org/10.1016/j.bmcl.2010.04.111

Creative Commons License
Creative Commons Attribution-Noncommercial-No Derivative Works 3.0
Citation Information
Stephen A. Kolodziej, Susan L. Hockerman, Gary A. DeCrescenzo, Joseph J. McDonald, et al.. "MMP-13 Selective Isonipecotamide Alpha-sulfone Hydroxamates" Bioorganic & Medicinal Chemistry Letters Vol. 20 Iss. 12 (2010)
Available at: http://works.bepress.com/daniel_p_becker/25/