Articles

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Radiation-Induced Galectin-1 by Endothelial Cells: A Promising Molecular Target for Preferential Drug Delivery to the Tumor Vasculature (with Meenakshi Upreti, Azemat Jamshidi-Parsian, Scott Apana, Marc Berridge, Nathan A. Koonce, Ralph L. Henry, and Robert J. Griffin), Journal of Molecular Medicine (2013)

The present study reports on a new strategy for selective, radiation therapy-amplified drug delivery using...

 

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Bi-Stability, Hysteresis, and Memory of Voltage-Gated Lysenin Channels (with Eric Krueger, Yuriy I. Mazur, Christine Stith, Yui Okuyama, Ralph Henry, and Greg J. Salamo), Biochimica et Biophysica Acta- Biomembranes (2011)

Lysenin, a 297 amino acid pore-forming protein extracted from the coelomic fluid of the earthworm...

 

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Potential Analytical Applications of Lysenin Channels for Detection of Multivalent Ions (with Redwan Al Faori, Eric Krueger, Yuriy I. Mazur, Matt Kern, Matt Williams, Amir Mortazavi, Ralph Henry, and Greg J. Salamo), Analytical and Bioanalytical Chemistry (2011)

Transmembrane protein transporters possessing binding sites for ions, toxins, pharmaceutical drugs, and other molecules...

 

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Multivalent Ions Control the Transport Through Lysenin Channels (with Eric Krueger, Redwan Al Faori, Rachel Lee, Yuriy I. Mazur, Ralph Henry, Mark Arnold, and Greg J. Salamo), Biophysical Chemistry (2010)

We report the effect of different ions on the conducting properties of lysenin channels inserted...

 

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Controlled Gating of Lysenin Pores (with Eric Krueger, Rachel Lee, Matt Naglak, Yuriy Mazur, Ralph Henry, and Greg Salamo), Biophysical Chemistry (2010)

Lysenin forms unitary large conductance pores in artificial bilayer membranes containing sphingomyelin. A population of...

 

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The Membrane-binding Motif of the Chloroplast Signal Recognition Particle Receptor (cpFtsY) Regulates GTPase Activity (with Naomi J. Marty, Dakshinamurthy Rajalingam, Alicia D. Kight, Nathaniel E. Lewis, Thallapuranam Krishnaswamy Suresh Kumar, Ralph L. Henry, and Robyn L. Goforth), Journal of Biological Chemistry (2009)

The chloroplast signal recognition particle (cpSRP) and its receptor (cpFtsY) function in thylakoid biogenesis to...

 

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DNA Conformation and Base Number Simultaneously Determined in a Nanopore (with Eric Brandin, James Uplinger, Daniel Branton, and Jiali Li), Electrophoresis (2007)

When dsDNA polymers containing identical number of base pairs were electrophoresed through a nanopore in...

 

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Electrical Characterization of Protein Molecules by a Solid-State Nanopore (with Bradley Ledden, David S. McNabb, and Jiali Li), Applied Physics Letters (2007)

The authors measured ionic current blockages caused by protein translocation through voltage-biased silicon nitride nanopores...

 

Contributions to Books

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Sensing Single Protein Molecules with Solid-State Nanopores (with Bradley Ledden, David S. Talaga, and Jiali Li), Nanopores: Sensing and Fundamental Biological Interactions (2011)

This chapter is focused on the development of experiments and theory of using solid-state nanopores...

 

Patents

Method of Controlled Drug Release from a Liposome Carrier, WO/2010/114901 (with Greg Salamo, Ralph Henry, Michael Borrelli, and Peter Corry) (2010)

Disclosed are methods and compositions for the controlled release of a drug or agent from...