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Selected Works of Clinton D Chapman
Article
Food dependence in rats selectively bred for low versus high saccharin intake. Implications for "food addiction".
Appetite (2011)
  • Clinton D Chapman, Occidental College
  • Nancy K Dess, Occidental College
  • Veronica Yakovenko
  • Elizabeth R Speidel
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Abstract
The "food addiction" concept implies that proneness to drug dependence and to food dependence should covary. The latter was studied in low- (LoS) and high- (HiS) saccharin-consuming rats, who differ in drug self-administration (HiS > LoS) and withdrawal (LoS > HiS). Sugary food intake in the first 1–2 h was higher in HiS than LoS rats. Sugar intake predicted startle during abstinence only among LoS rats. These results may suggest bingeing-proneness in HiS rats and withdrawal-proneness among LoS rats. However, intake escalation and somatic withdrawal did not differ between lines. Further study with selectively bred rats, with attention to definitions and measures, is warranted.
Keywords
  • food dependence,
  • rats,
  • saccharin intake,
  • food addiction
Disciplines
Publication Date
October, 2011
Citation Information
Clinton D Chapman, Nancy K Dess, Veronica Yakovenko and Elizabeth R Speidel. "Food dependence in rats selectively bred for low versus high saccharin intake. Implications for "food addiction"." Appetite Vol. 57 Iss. 2 (2011)
Available at: http://works.bepress.com/clinton_chapman/2/