We comment on 6 clinical cases involving the application of one or more elements of Motivational Interviewing (MI). First, we share our general reactions to MI and the case material. Second, we reflect briefly and specifically on each case illustration, highlighting the compelling flexibility and clinical utility of the MI spirit and its principles. Third, we offer several reflective themes across the cases, including convergences between MI and other psychotherapies, and unanswered clinical questions related to MI, its effectiveness, and its change mechanisms. FInally, we advance a context-responsive psychotherapy integration for which MI might effectively serve as the bellwether.