Selected Recent Publications
A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both α- and β-ketone reduction during chain growth (with Stephanie B. Bumpus, Neil L. Kelleher, Christopher T. Walsh, and Nathan A. Magarvey), PNAS (2008)
Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis (with Stephanie B. Bumpus, Nathan A. Magarvey, Neil L. Kelleher, and Cristopher T. Walsh), Journal of the American Chemical Society (2008)
Polyketide biosynthesis is typically directed by cis-acting catalytic domains. In the case of the Bacillus...