Friendships are beneficial to individual happiness. Studies have examined virtual relationships; however, the quality and utility of adult, online gaming friendships and their relationship with happiness is still not well understood. Respondents were surveyed about friendship quality with their closest friends across two modalities (face-to-face or online via gaming), as well as other relationship characteristics including communication frequency and friendship length. We identified a statistically significant difference between the modalities in friendship quality. We also identified a relationship between friendship quality and happiness. We discuss these results in terms of practical implications concerning friendship quality in face-to-face and online gaming best friendships and their influence on happiness.