Articles

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Experimental Versus Numerical Data for Breast Cancer Progression (with M. Kolev, Ken Tawara, and Barbara Zubik-Kowal), Nonlinear Analysis: Real World Applications (2012)

This paper deals with a mouse model of breast cancer based on two mammary adenocarcinoma...

 

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Clinical Significance of Interleukin (IL)-6 in Cancer Metastasis to Bone: Potential of Anti-IL-6 Therapies (with Ken Tawara and Julia T. Oxford), Cancer Management and Research (2011)

Metastatic events to the bone occur frequently in numerous cancer types such as breast, prostate,...

 

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Kinetics of DNA and RNA Hybridization in Serum and Serum-SDS (with Elton Graugnard, Amber Cox, Jeunghoon Lee, Bernard Yurke, and William L. Hughes), IEEE Transactions on Nanotechnology (2010)

Cancer is recognized as a serious health challenge both in the United States and throughout...

 

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Correlation Between Animal and Mathematical Models for Prostate Cancer Progression (with Z. Jackiewiczy, M. Kolevx, and Barbara Zubik-Kowal), Computational & Mathematical Methods in Medicine (2009)

This work demonstrates that prostate tumour progression in vivo can be analysed by using solutions...

 

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Collagen a1(XI) in Normal and Malignant Breast Tissue (with Karen C. Halsted, Kara B. Bowen, Laura Bond, Sarah E. Luman, William E. Fyffe, Joseph D. Kronz, and Julia T. Oxford), Modern Pathology (2008)

Little is known about collagen XI expression in normal and malignant breast tissue. Tissue microarrays,...

 

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Oncostatin M Induces Cell Detachment and Enhances the Metastatic Capacity of T-47D Human Breast Carcinoma Cells (with Ryan G. Holzer and Randall E. Ryan), Cytokine (2006)

Oncostatin M (OSM), an IL-6 family cytokine, has previously been shown to increase migration of...

 

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Breast Cancer Cells Stimulate Neutrophils to Produce Oncostatin M: Potential Implications for Tumor Progression (with Marisa M. Queen, Randall E. Ryan, Ryan G. Holzer, and Cynthia R. Keller-Peck), Cancer Research (2005)

Tumor-associated and tumor-infiltrating neutrophils (TAN) and macrophages (TAM) can account for as much as 50%...

 

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Involvement of HGF/SF–Met Signaling in Prostate Adenocarcinoma Cells: Evidence for Alternative Mechanisms Leading to a Metastatic Phenotype in Pr-14c (with Christina MacDougall, Micaela Vargas, Colin R. Soares, Ryan G. Holzer, and Alexander E. Ide), The Prostate (2005)

BACKGROUND

Hepatocyte growth factor/scatter factor (HGF/SF) facilitates intercellular communication between the epithelial carcinoma and its...

 

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Oncostatin M Stimulates the Detachment of a Reservoir of Invasive Mammary Carcinoma Cells: Role of Cyclooxygenase-2 (with Ryan G. Holzer, Randall E. Ryan, Matt Tommack, and Eric Schlekeway), Clinical and Experimental Metastasis (2004)

Previously, oncostatin M (OSM) has been shown to inhibit the proliferation of breast cancer cells...

 

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Development and Characterization of a Progressive Series of Mammary Adenocarcinoma Cell Lines Derived from the C3(1)/SV40 Large T-antigen Transgenic Mouse Model (with Ryan G. Holzer, Christina MacDougall, Gerry Cortright, Kristi Atwood, and Jeffrey E. Green), Breast Cancer Research and Treatment (2003)

We have developed four new mammary adenocarcinoma cell lines from the C3(1)/SV40 Large T-antigen (Tag)...

 

Presentations

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Operation of a DNA-Based Autocatalytic Network in Serum (with Elton Graugnard, Amber Cox, Jeunghoon Lee, Bernard Yurke, and William L. Hughes), 16th International Conference on DNA Computing and Molecular Programming (2010)

The potential for inferring the presence of cancer by the detection of miRNA in human...

 

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Point-of-Contact, DNA-Based Amplifier for Detecting Cancer-Related Micro-RNA in Blood Serum (with Elton Graugnard, Amber Cox, Jeunghoon Lee, Bernard Yurke, and William L. Hughes), 7th Annual Foundations of Nanoscience: Self-Assembled Architectures and Devices (2010)
 

Student Mentored Work

Development of Bioluminescent Mammary Cancer Cells with Knocked Down Expression of OSM for Detection of Bone Metastasis in Vivo (with Caleb Sutherland, Ken Tawara, and Jeff Reshaw), Podium Presentations (2010)

Oncostatin M (OSM) is a multifunctional cytokine belonging to the interleukin (IL)-6 subfamily. OSM was...

 

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Biology of Cancer Class Metastasizes Knowledge (with Chris Barbey, Madeline Connley, Ben Davis, Rachel Hightower, Jon Reeck, and Caleb Sutherland), Service-Learning Program (2010)

Cancer, in all its forms, is a leading cause of death and serious disease. The...