The statistics are sobering: 1 in 8 women will get breast cancer, a devastating disease that can metastasize to the liver, lungs, brain and bone. Jorcyk discusses how breast cancer develops and spreads, current therapies, the challenges involved in a finding a cure, and her research program. The recipient of grants from the American Cancer Society, the Susan G. Komen Foundation, the National Institutes of Health and NASA, Jorcyk is investigating a signaling molecule called Oncostatin M that is produced by breast cancer cells and tumor-associated cells of the immune system, and that may contribute to the progression and spread of tumors.