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Selected Works of Charles A. Sanislow, Ph.D.
Article
Methodological considerations for treatment trials for persons with borderline personality disorder
Annals of Clinical Psychiatry (2010)
  • Mary C. Zanarini, Harvard Medical School
  • Barbara Stanley
  • Donald W. Black
  • John C. Markowitz
  • Marianne Goodman
  • Paul Pilkonis, University of Pittsburgh
  • Thomas R. Lynch, University of Exeter
  • Kenneth Levy, The Pennsylvania State University
  • Peter Fonagy, University College London
  • Martin Bohus
  • Joan Farrell
  • Charles A. Sanislow, Wesleyan University
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Abstract

BACKGROUND: The National Institute of Mental Health convened an international group of experts to examine the conduct of treatment trials for persons with borderline personality disorder (BPD). The rapid growth of treatment research had led to the recognition that investigators face unique methodological issues with these challenging patients.

METHODS: Conference members reviewed critical aspects of psychotherapy and pharmacotherapy trial design for patients with BPD.

RESULTS: This article summarizes discussions held on March 17-18, 2005.

CONCLUSION: This paper addresses the most pressing issues in sample selection and trial design pertaining to BPD; issues that have bedeviled both investigators submitting applications and reviewers trying to assess the merit of these grants. By disseminating this work, conference members hope to make this process more consistent and productive for all concerned.

Keywords
  • Borderline,
  • borderline personality,
  • borderline personality disorder,
  • treatment,
  • treatment trials,
  • treatment trial methodology,
  • guidelines for BPD treatment trials
Disciplines
Publication Date
May, 2010
Citation Information
Zanarini, M. C., Stanley, B., Black, D. W., Markowitz, J. C., Goodman, M., Pilkonis, P., Lynch, T. R., Levy, K., Fonagy, P., Bohus, M., Farrell, J., & Sanislow, C. A. (2010). Methodological considerations for treatment trials for persons with borderline personality disorder. Annals of Clinical Psychiatry, 22(2), 75-83.