This chapter reports on an ethnographic study of the experiences, practices and feelings of academic librarians who teach information literacy. Based on in-depth interviews with nine librarians who have information literacy responsibilities – five in West Virginia and four in Colorado – it examines the real-life work of practitioners in a wide variety of instructional environments. The research considers participants’ preparation for their instructional role, ambiguity about the concept of information literacy, instructional challenges and professional practices. The authentic voices of instructional librarians provide insights into the roadblocks they face, success they experience and their expectations for the future.