Our group, the Optical Science Laboratory (OSL) is particularly interested in those optical imaging techniques which involve coherent detection, multi-modal imaging, multi-wave imaging (where light is used in combination with another type of wave such as ultrasound). Our applications include biological and medical imaging, including embryos, skin, collagen, and lung.
Arthritis
Using diffuse optical tomography with acoustic photonic imaging (with Blair Simon), Research Thrust R1 Presentations (2007)
The goal of this work is to provide useful information about arthritic joints using a...
Imaging systems
Component extraction from CRM skin images (with Sol M. Cruz Rivera and Vidya Manian), Research Thrust R2 Presentations (2007)
Confocal Reflectance Microscope images the skin in 4 dimensions. The third and fourth dimensions being...
Compact dual wedge point scanning confocal reflectance microscope (with William C. Warger II and Stephen A. Guerrera), I-PLUS Presentations (2006)
Confocal reflectance microscopy has been shown to provide optical sectioning and resolution sufficient to provide...
FDTD simulation of a confocal microscope using a theta line scan (with Blair Simon, Milind Rajadhyaksha, and Carey Rappaport), I-PLUS Presentations (2006)
We describe a 2-D computational model of the optical propagation in human skin from a...
Photo-thermal coherent confocal microscope (with Sean Sullivan), I-PLUS Presentations (2006)
Confocal microscopy has been shown to be useful in imaging skin slightly below the junction...
Confocal microscopy
Compact dual wedge point scanning confocal reflectance microscope (with William C. Warger II and Stephen A. Guerrera), I-PLUS Presentations (2006)
Confocal reflectance microscopy has been shown to provide optical sectioning and resolution sufficient to provide...
FDTD simulation of a confocal microscope using a theta line scan (with Blair Simon, Milind Rajadhyaksha, and Carey Rappaport), I-PLUS Presentations (2006)
We describe a 2-D computational model of the optical propagation in human skin from a...
Photo-thermal coherent confocal microscope (with Sean Sullivan), I-PLUS Presentations (2006)
Confocal microscopy has been shown to be useful in imaging skin slightly below the junction...
Biopsy
Articulating confocal endoscope for imaging cancers in vivo (with Gary Peterson, Michael Prince, Frank DiBella, and Melind Rajadhyaksha), BioBED Presentations (2007)
Skin cancers are among the highest incidence cancers, with 1.2 million new cases detected each...
Three-dimensional imaging
Adding polarimetric multiphotoniImaging to the W. M. Keck 3-dimensional fusion microscope (with Matthew B. Bouchard, William C. Warger II, and Gary S. Laevksy), BioBED Presentations (2007)
The W. M. Keck 3-Dimensional Fusion Microscope's (3DFM) multimodal imaging platform provides researchers the unique...
A new approximate model for microscopy imaging (with Heidy Sierra and Dana Brooks), Research Thrust R1 Presentations (2007)
There has been increasing interest in recent years in techniques for microscopic examination of optically...
Multi-spectral reflectance confocal microscopy on skin (with Tianchen Shi), Research Thrust R2 Presentations (2007)
Reflectance confocal microscopy is a powerful in-vivo modality for imaging superficial layers of biological tissue,...
Diagnostic imaging
Multi-spectral reflectance confocal microscopy on skin (with Tianchen Shi), Research Thrust R2 Presentations (2007)
Reflectance confocal microscopy is a powerful in-vivo modality for imaging superficial layers of biological tissue,...
Epidermis - Imaging
Compact dual wedge point scanning confocal reflectance microscope (with William C. Warger II and Stephen A. Guerrera), I-PLUS Presentations (2006)
Confocal reflectance microscopy has been shown to provide optical sectioning and resolution sufficient to provide...
FDTD simulation of a confocal microscope using a theta line scan (with Blair Simon, Milind Rajadhyaksha, and Carey Rappaport), I-PLUS Presentations (2006)
We describe a 2-D computational model of the optical propagation in human skin from a...
Photo-thermal coherent confocal microscope (with Sean Sullivan), I-PLUS Presentations (2006)
Confocal microscopy has been shown to be useful in imaging skin slightly below the junction...
Algorithms
Phase unwrapping using reconfigurable hardware (with Sherman Braganza, Miriam Leeser, W. C. Warger II, and C. M. Warner), Research Thrust R3 Presentations (2007)
The most computationally intensive part of the minimum LP Norm phase unwrapping algorithm[1] (its kernel)...
Cancer--Diagnosis
Articulating confocal endoscope for imaging cancers in vivo (with Gary Peterson, Michael Prince, Frank DiBella, and Melind Rajadhyaksha), BioBED Presentations (2007)
Skin cancers are among the highest incidence cancers, with 1.2 million new cases detected each...
Multi-spectral reflectance confocal microscopy on skin (with Tianchen Shi), Research Thrust R2 Presentations (2007)
Reflectance confocal microscopy is a powerful in-vivo modality for imaging superficial layers of biological tissue,...
Anisotropy
Adding polarimetric multiphotoniImaging to the W. M. Keck 3-dimensional fusion microscope (with Matthew B. Bouchard, William C. Warger II, and Gary S. Laevksy), BioBED Presentations (2007)
The W. M. Keck 3-Dimensional Fusion Microscope's (3DFM) multimodal imaging platform provides researchers the unique...
Diagnostic ultrasonic imaging
Using diffuse optical tomography with acoustic photonic imaging (with Blair Simon), Research Thrust R1 Presentations (2007)
The goal of this work is to provide useful information about arthritic joints using a...
Confocal microscopy--Technological innovations
Improving the data acquisition of the dual-wedge confocal microscope (with Stephen A. Guerrera and William C. Wargar II), Research Thrust R1 Presentations (2007)
A new method of generating images from the dual-wedge confocal microscope was developed. The previous...