ABSTRACT. Health science librarians experience challenges when partnering with people from other professional backgrounds such as nursing and with people of different ages. In partnering with people of other backgrounds,it is helpful to recognize the changing nature of research skills and the fact that many 21st century college students lack a print-based concept of research. Helping students to succeed in understanding and participating in the research process is more important than ever due to changes in the nursing profession, the sheer mass of scholarly information, and the challenges of searching for information on the world wide web.