The occupational health and safety conditions of a sample of Brazilian housecleaners in Massachusetts are examined in this article. We administered a main survey to a convenience sample of 626 Brazilian immigrant workers of all trades and a supplemental survey to 163 Brazilian housecleaners in Massachusetts in 2005 and 2006. Survey questions addressed housecleaner demographics, socioeconomic status, working conditions, and hazards of housecleaning work. Housecleaners are exposed to a variety of ergonomic, chemical, and biological hazards. Professional housecleaners’ work is fastpaced, requires awkward postures, and involves repetitive movements, use of force, and heavy lifting. The most common symptoms reported include back pain, and pain in the muscles, arms, legs, neck, shoulder, hands, fingers, and feet. To reduce exposures to occupational hazards, we propose the substitution of green cleaners for toxic chemical cleaning products, the use of ergonomic equipment, the use of personal protective equipment, and changes in work organization.