My current research interests include determination of PLC zeta (PLCζ) concentration
in sperm of dogs and equine and how it relates to fertility. Some cases of male
infertility, especially those associated with normal sperm numbers and motility may be
caused by decreased amounts of a factor(s) in the sperm responsible for inducing egg
activation and initiation of embryo development. Less than optimal fertility may be also
explained by decreased amounts of this protein in sperm. This putative factor is likely
to be the recently identified PLCζ. We are securing specimens of infertile dogs and
stallions that visit our services as has been recently published in: C. Gradil, S-Y.
Yoon, J. Brown, C. He, P. Visconti, R. Fissore. 2006. PLCζ: a marker of fertility for
stallions? Animal Reproduction Science 94:23-25. 

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Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare (with L. Frederico, M. Gerard, and C. Pinto), Canadian Veterinary Journal (2007)

An Arabian mare was referred for right granulosa-theca cell tumor (GTCT) evaluation. The mare was...

 

PLCζ: a marker of fertility for stallions? (with J. Yoon, C. Brown, P. He, and R. Fissore), Animal Reproduction Science (2006)

Fertilization of eggs from all species studied to date is characterized by an increase in...

 

Leukocytes trapped in the fetal membranes of newborn foals (with D.H. Volkmann, R.O. Gilbert, and R. Linke), Theriogenology (2002)

Upon the delivery of a foal’s pelvis at the end of stage 2 of labor,...

 

Pregnancy Diagnosis in the Bitch (with A. Yeager and P. Concannon), Kirk’s Current Veterinary Therapy (2000)
 

The use of pentoxifylline to improve motility of cryopreserved equine spermatozoa (with B.A. Ball), Theriogenology (2000)

Pentoxifylline was evaluated as a method to increase motility of cryopreserved equine spermatozoa. In a...