Endo-Porter–Mediated Delivery of Phosphorodiamidate Morpholino Oligos (PMOs) in Erythrocyte Suspension Cultures from Cope's Gray Treefrog Hyla Chrysoscelis
(Venkateshwar Mutyam, Matthew V. Puccetti, James Frisbie, et al.)
BioTechniques
(2011)
Cope's gray treefrog, Hyla chrysoscelis, is a freeze-tolerant anuran that accumulates cryoprotective glycerol during cold acclimation. H. chrysoscelis erythrocytes express the aquaglyceroporin HC-3, which facilitates transmembrane glycerol and water movement. Aquaglyceroporins have no pharmacological inhibitors, ...