After completing his Ph.D. in biostatistics under the supervision of Dr. Mark van der Laan, Oliver joined the biostatistics faculty at the University of California, Berkeley, as an Assistant Adjunct Professor. At the same time, he started working for Target Analytics, a recent start-up company that is based on the premise of making state-of-the-art causal inference methodology available to a wide audience of users. In this position, he has been designing and programming the statistical engine for the first software product to be released by Target Analytics. He has also been consulting a development-stage pharmaceutical company on a drug trial that had failed to gain FDA approval. When he revealed a subgroup of patients for whom the drug in question was highly effective, the company was re-capitalized to conduct a new trial. Recently, he gave up his faculty position at Berkeley to devote more time to his work at Target Analytics.
Articles
Statistical Methods for Analyzing Sequentially Randomized Trials (with Mark J. van der Laan), Journal of the National Cancer Institute (2007)
In this issue of JNCI, Thall et al. present the results of a clinical trial...
Data-adaptive estimation of the treatment-specific mean (with Yue Wang and Mark van der Laan), Journal of Statistical Planning and Inference (2007)
An important problem in epidemiology and medical research is the estimation of the causal effect...
Supervised detection of conserved motifs in DNA sequences with cosmo (with Sunduz Keles and Mark J. van der Laan), Statistical Applications in Genetics and Molecular Biology (2007)
A number of computational methods have been proposed for identifying transcription factor binding sites from...
A practical illustration of the importance of realistic individualized treatment rules in causal inference (with Mark J. van der Laan), Electronic Journal of Statistics (2007)
The effect of vigorous physical activity on mortality in the elderly is difficult to estimate...
Asthma awareness/evironmental practices in childcare centers (with Michelle G. Goveia, Nazerah Shaikh, Gayle Windham, Katherine Feldman, and Richard Kreutzer), Pediatric Asthma, Allergy and Immunology (2005)
Asthma prevalence is increasing. Child care centers can play an important role in controlling asthma...
Contributions to Books
Identifying important explanatory variables for time-varying outcomes. (with Maya L. Petersen and Mark J. van der Laan), Fundamentals of Data Mining in Genomics and Proteomics (2006)
This chapter describes a systematic and targeted approach for estimating the impact of each of...
Technical Reports
Biomarker discovery using targeted maximum likelihood estimation: Application to the treatment of antiretroviral resistant HIV infection (with Maya L. Petersen, Soo-Yon Rhee, W. Jeffrey Fessel, Sandra E. Sinisi, Robert W. Shafer, and Mark J. van der Laan) (2007)
Researchers in clinical science and bioinformatics frequently aim to learn which of a set of...
Analyzing Sequentially Randomized Trials based on Causal Effect Models for Realistic Individualized Treatment Rules (with Mark J. van der Laan), U.C. Berkeley Division of Biostatistics Working Paper Series (2007)
In this paper, we argue that causal effect models for realistic individualized treatment rules represent...
Estimating the Effect of Vigorous Physical Activity on Mortality in the Elderly Based on Realistic Individualized Treatment and Intention-to-Treat Rules (with Mark J. van der Laan), U.C. Berkeley Division of Biostatistics Working Paper Series (2007)
The effect of vigorous physical activity on mortality in the elderly is difficult to estimate...
The causal effect of recent leisure-time physical activity on all-cause mortality among the elderly (with Mark J. van der Laan and Ira B. Tager), U.C. Berkeley Division of Biostatistics Working Paper Series (2007)
We analyze data collected as part of a prospective cohort study of elderly people living...
Software
cosmoGUI: An R package for interactively constructing constraint sets as used by the cosmo R package. (with Fabian Gallusser and Sandrine Dudoit) (2007)
cosmoGUI allows the user to interactively define constraint sets that can be used by the...
seqLogo: An R package for plotting DNA sequence logos. (2007)
seqLogo takes the position weight matrix of a DNA sequence motif and plots the corresponding...
cosmo: An R package for the supervised detection of conserved motifs in DNA sequences. (with Fabian Lee Gallusser and Sandrine Dudoit) (2006)
cosmo searches a set of unaligned DNA sequences for a shared motif that may, for...
cosmoweb: A web application for the supervised detection of conserved motifs in DNA sequences. (with Sunduz Keles and Mark Johannes van der Laan) (2006)
cosmo searches a set of unaligned DNA sequences for a shared motif that may, for...
ccosmo: A stand-along C program for the supervised detection of conserved motifs in DNA sequences. (with Sunduz Keles and Mark Johannes van der Laan) (2006)
cosmo searches a set of unaligned DNA sequences for a shared motif that may, for...