Alterations in bovine serum biochemistry profiles associated with prolonged consumption of endophyte-infected tall fescue
The serum biochemistry profiles from 8 cattle that grazed endophyte (Neotyphodium coenophialum)-infected tall fescue (Festuca arundinacea) (E+TF) were compared with those from 8 control cattle that grazed on endophyte-free tall fescue (E-TF). Cattle were bled on 7 dates between April and August 1996 and on 5 dates between May and July 1997. Cattle that grazed E+TF retained rough winter haircoats and had lesser weight gains compared with those grazing E-TF. They had decreased activities of alkaline phosphatase and alanine aminotransferase. Compared with controls, they had lower values for serum prolactin and globulin concentrations. The concentration of creatinine and the albumin/globulin ratio were increased in the cattle grazing E+TF. Isozyme determination of alkaline phosphatase indicated that the decrease in serum activity of cattle grazing E+TF was due to decreases in both intestinal and bone isozymes. Serum protein electrophoresis indicated that the decrease in serum globulin concentration was due to decreases in both α and γ globulin fractions of this protein.
A E. Schultze, Barton W. Rohrbach Dr., H A. Fribourg, J C. Waller, and Jack W. Oliver. "Alterations in bovine serum biochemistry profiles associated with prolonged consumption of endophyte-infected tall fescue" Veterinary and Human Toxicology 41.3 (1999): 133-139.
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