Correlation Between Animal and Mathematical Models for Prostate Cancer Progression

Z. Jackiewiczy, Arizona State University
Cheryl L. Jorcyk, Boise State University
M. Kolevx, University of Warmia and Mazury
Barbara Zubik-Kowal, Boise State University

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This is an electronic version of an article published in Computational and Mathematical Methods in Medicine, 10(4). Computational and Mathematical Methods in Medicine is available online at: http://www.informaworld.com/smpp. DOI: 10.1080/17486700802517518

Abstract

This work demonstrates that prostate tumour progression in vivo can be analysed by using solutions of a mathematical model supplemented by initial conditions chosen according to growth rates of cell lines in vitro. The mathematical model is investigated and solved numerically. Its numerical solutions are compared with experimental data from animal models. The numerical results confirm the experimental results with the growth rates in vivo.