Article
Self-Immolative Phthalate Esters Sensitive to Hydrogen Peroxide and Light
The Journal of Organic Chemistry
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
11-10-2014
DOI
10.1021/jo501900h
Abstract
Self-immolative aryl phthalate esters were conjugated with cleavable masking groups sensitive to light and hydrogen peroxide. The phthalate linker releases the fluorescent dye 7-hydroxycoumarin upon exposure to light or H2O2, respectively, leading to an increase in fluorescence. The light-sensitive aryl phthalate ester is demonstrated as a pro- fluorophore in cultured S2 cells
Copyright Owner
American Chemical Society
Copyright Date
2014
Language
en
File Format
application/pdf
Citation Information
Kaitlyn M. Mahoney, Pratik P. Goswami, Aleem Ayed, Patrick Kolker, et al.. "Self-Immolative Phthalate Esters Sensitive to Hydrogen Peroxide and Light" The Journal of Organic Chemistry Vol. 79 Iss. 23 (2014) p. 11740 - 11743 Available at: http://works.bepress.com/arthur_winter/24/
Reprinted (adapted) with permission from The Journal of Organic Chemistry, 79(23); 11740-11743. Doi: 10.1021/jo501900h. Copyright 2014 American Chemical Society.