I study the neural systems that regulate energy balance, neuroendocrine function and
behavioral state in the mammalian brain. I am particularly interested in the
intracellular signaling mechanisms used by various neurotransmitters within hypothalamic
circuits participating in feeding and sleep/wake behaviors, and how these mechanisms
might be influenced by nutrient status (e.g., hypoglycemia). 

I also collaborate on neuroinformatics projects related to the modeling and management of
neuroscientific data about these circuits. As part of my interests in mechanisms
underlying nutrient homeostasis, I also maintain an active research interest in the
history of neurochemistry and thermodynamics. 

As part of my scientific duties, I am strongly committed to classroom and laboratory
instruction in the life sciences (biology, biochemistry, neuroscience) at the college and
university level.

Neural Circuits Responsive to Changes in Blood Sugar

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MAP Kinases Couple Hindbrain-Derived Catecholamine Signals to Hypothalamic Adrenocortical Control Mechanisms during Glycemia-Related Challenges (with Kimberly L. Kaminski, Graciela Sanchez-Watts, Todd A. Ponzio, J. Brent Kuzmiski, Jaideep S. Bains, and Alan G. Watts), The Journal of Neuroscience (2011)
 

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A Role for the Forebrain in Mediating Time-of-Day Differences in Glucocorticoid Counterregulatory Responses to Hypoglycemia in Rats (with Lori M. Gorton, MaryAnn Bohland, Graciela Sanchez-Watts, Casey M. Donovan, and Alan G. Watts), Endocrinology (2007)
 

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Catecholaminergic Control of Mitogen-Activated Protein Kinase Signaling in Paraventricular Neuroendocrine Neurons In Vivo and In Vitro: A Proposed Role during Glycemic Challenges (with Todd A. Ponzio, Graciela Sanchez-Watts, B. Glenn Stanley, Glenn I. Hatton, and Alan G. Watts), The Journal of Neuroscience (2007)
 

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Intravenous 2-Deoxy-D-Glucose Injection Rapidly Elevates Levels of the Phosphorylated Forms of p44/42 Mitogen-Activated Protein Kinases (Extracellularly Regulated Kinases 1/2) in Rat Hypothalamic Parvicellular Paraventricular Neurons (with Alan G. Watts), Endocrinology (2004)
 

Neural Controls of Food Intake and Body Weight Regulation

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Activation in neural networks controlling ingestive behaviors: What does it mean, and how do we map and measure it? (with Alan G. Watts, Graciela Sanchez-Watts, Dawna Salter, and Christina M. Neuner), Physiology & Behavior (2006)
 

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Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions of Src Family Tyrosine Kinases to Feeding Triggered Either by NMDA Injection or by Food Deprivation (with Herman H. Cheung, Elizabeth R. Gillard, Jennifer A. Palarca, Derek S. Welsbie, James W. Gurd, and B. Glenn Stanley), The Journal of Neuroscience (2004)
 

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Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: immunochemical/behavioral evidence (with Margarita C. Curras, Jennifer Dao, Faizi A. Jamal, Rishi K. Goel, Elizabeth R. Gillard, Stefany D. Wolfsohn, and B. Glenn Stanley), American Journal of Physiology - Regulatory, Integrative, and Comparative Physiology (1999)
 

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The Second Messenger cAMP Elicits Eating by an Anatomically Specific Action in the Perifornical Hypothalamus (with Elizabeth R. Gillard, Rickinder S. Grewal, Bara Mouradi, Stefany D. Wolfsohn, and B. Glenn Stanley), The Journal of Neuroscience (1998)
 

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Eating induced by perifornical cAMP is behaviorally selective and involves protein kinase activity (with Elizabeth R. Gillard, Bara Mouradi, Omkar Nalamwar, and B. Glenn Stanley), American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (1998)
 

Protein Expression Patterns in the Brain

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N-Methyl-D-Aspartate Receptor Subunit NR2B Is Widely Expressed Throughout the Rat Diencephalon: An Immunohistochemical Study (with B. Glenn Stanley, Lisa Bozzetti, Christina Chin, Cyndi Stivers, and Margarita Curras-Collazo), Journal of Comparative Neurology (2000)
 

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Colocalization of calretinin and calbindin-D28k with oxytocin and vasopressin in rat supraoptic nucleus neurons: A quantitative study (with Seiji Miyata and Glenn I. Hatton), Brain Research (1998)
 

Neuroinformatics

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NeuroScholar’s Electronic Laboratory Notebook and Its Application to Neuroendocrinology (with Joel D. Hahn, We-Cheng Cheng, Alan G. Watts, and Gully APC Burns), Neuroinformatics (2006)
 

History of Neuroscience and Bioenergetics

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Nerve, Muscle, Blood, Toil, Tears, and Sweat: England’s Pioneering Biophysicist, Soldier, and Statesman, Journal of the History of the Neurosciences (2009)