Genetics
Genetics and cardiovascular disease: Design and development of a DNA biobank, Experimental and clinical cardiology (2009)
Coronary artery disease (CAD) is a complex disease with environmental and genetic determinants. Many other...
Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation (with Justin Graf and Richard Hodgson), Human mutation (2005)
Human physical pigmentation is determined by the type and amount of melanin and the process...
No subject area
Assessment of DNA degradation and the genotyping success of highly degraded samples (with Sheree R. Hughes-Stamm and Kevin J. Ashton), International journal of legal medicine (2011)
DNA becomes progressively more fragmented as biological tissue degrades resulting in decreasing ability to gain...
The DRD2 gene 957C>T polymorphism is associated with Posttraumatic Stress Disorder in war veterans (with Joanne Voisey, Christopher D. Swagell, Ian P. Hughes, C. Phillip Morris, Earnest P. Noble, Burnett Kann, Karen A. Heslop, Ross McD Young, and Bruce R. Lawford), Depression and anxiety (2009)
Background: Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders...
Forensically relevant SNP classes (with Bruce Budowle), BioTechniques: The international journal of life science methods (2008)
Forensic samples that contain too little template DNA or are too degraded require alternate genetic...
A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA (with Joanne Voisey, Maria del C. Gomez-Cabrera, D. J. Smit, J. Helen Leonard, and Rick A. Sturm), Health Sciences & Medicine papers (2006)
To date, a role for agouti signalling protein (ASIP) in human pigmentation has not been...
Association of functionally different RUNX2 P2 promoter alleles with BMD (with James D Doecke, Christopher J. Day, Alexandre SJ Stephens, Shea L. Carter, Mark A. Kotowicz, Geoff C. Nicholson, and Nigel A. Morrison), Journal of Bone and Mineral Research (2006)
RUNX2 gene SNPs were genotyped in subjects from the upper and lower deciles of age-...
Gene polymorphisms and their effects in the melanocortin system (with Levi J. Carroll and Joanne Voisey), Peptides (2005)
In addition to its role in human pigmentation, components of the melanocortin system regulate appetite,...
Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape (with Anna K. Coussens), Genomics (2005)
Mutations in FGFR1 and TWIST1 have been reported to affect the timing of calvarial suture...
The C/C genotype of the C957T polymorphism of the dopamine D2 receptor (DRD2) is associated with schizophrenia (with Bruce R. Lawford, Ross McD Young, Christopher D. Swagell, Mark Barnes, Simon C. Burton, Warren K. Ward, Karen R. Heslop, Susan Shadforth, Angela van Daal, and C Phillip Morris), Schizophrenia Research (2005)
The T allele of the human dopamine D2 receptor (DRD2) gene C957T polymorphism is associated...
Mouse models of obesity (with Carroll Levi and Joanne Voisey), Clinics in Dermatology (2004)
Insights into the etiology of human obesity have arisen from the study of animal models....
Melanocortins and their receptors and antagonists (with J Voisey and L Carroll), Current Drug Targets (2003)
The melanocortins are a group of small protein hormones derived by post-translational cleavage of the...
Agouti signal protein regulation in human melanoma cells (with Joanne Voisey, Greg Kelly, and Angela van Daal), Pigment Cell Research (2003)
Production of the pigment eumelanin is controlled by α-melanocyte stimulating hormone (α-MSH) stimulation of melanocortin...
Identification and minisequencing-based discrimination of SHV β-lactamases in nosocomial infection-associated Klebsiella pneumoniae in Brisbane, Australia (with Christopher Howard, Gregory Kelly, Jacqueline Schooneveldt, Graeme Nimmo, and Philip M. Giffard), Antimicrobial agents and chemotherapy (2002)
Extended-spectrum B-lactamases (ESBLs) are active against oxyimino cephalosporins and monobactams. Twenty-one Klebsiella pneumoniae isolates obtained...
Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens (with J Inman-Bamber, C Wan, T Gardam, R Vohra, and P Timms), Molecular and Cellular Probes (2002)
We report the development of a microtitre plate-based PCR-EIA assay (ELAHA; Enzyme Linked Amplification and...
Agouti: From mouse to man, from skin to fat (with Joanne Voisey and Angela van Daal), Pigment Cell Research (2002)
The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with...
Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific (with Joanne Voisey, Pascal Imbeault, Louise Hutley, John B. Prins, and Angela van Daal), Obesity Research (2002)
OBJECTIVE: To determine if human adipocyte agouti signal protein (ASIP) mRNA expression is associated with...
Interrogation of multimeric DNA amplification products by competitive primer extension using Bst DNA polymerase (large fragment) (with J Voisey, G Hafner, C Morris, and P Giffard), BioTechniques (2001)
Linear dsDNA composed of tandem repeats may, be exponentially amplified by the strongly strand-displacing Bst...
A polymorphism study of the human agouti gene and its association with MC1R (with Joanne Voisey, Neil Box, and Angela van Daal), Pigment Cell Research (2001)
To determine whether the Agouti Signalling Protein (ASP) gene is associated with skin and hair...
Solid-phase amplification and detection: A single-tube diagnostic assay for infectious agents (with Maria Somodevilla-Torres , Peter Timms, Ray Harris , Phillip Morris, and Angela van Daal ), Molecular Diagnosis (2001)
BACKGROUND: We report the development of an enzyme-linked immunosorbent assay[mdash ]like single-tube assay for the...