Reverse Transcriptase Polymerase Chain Reaction

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Humans

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Time Factors

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Disease Modeling

Validation and Discovery in Markov Models of Genetics Data (with Victor De Gruttola), Statistical Applications in Genetics and Molecular Biology (2012)

Markov models provide a natural framework for modeling cellular and molecular level changes over time....

 

Mothers

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Multivariate Analysis

Reader Reaction (with Victor De Gruttola), Statistical Applications in Genetics and Molecular Biology (2012)

This note is a response to the article "relating HIV-1 sequence variation to replication capacity...

 

Female

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Adolescent

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

General Biostatistics

Ridge Regression for Longitudinal Biomarker Data (with Melissa Eliot, Jane Ferguson, and Muredach P. Reilly), The International Journal of Biostatistics (2012)

Technological advances facilitating the acquisition of large arrays of biomarker data have led to new...

 

A Resampling-Based Approach to Multiple Testing with Uncertainty in Phase (with Victor G. DeGruttola), The International Journal of Biostatistics (2012)

Characterizing the genetic correlates to complex diseases requires consideration of a large number of potentially...

 

An Expectation Maximization Approach to Estimate Malaria Haplotype Frequencies in Multiply Infected Children (with Xiaohong Li, Recai M. Yucel, and Stephen M. Rich), Statistical Applications in Genetics and Molecular Biology (2012)

Characterizing genetic variability in the human pathogenic Plasmodium species, the group of parasites that cause...

 

Genotype

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Male

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Computational Biology/Bioinformatics

Validation and Discovery in Markov Models of Genetics Data (with Victor De Gruttola), Statistical Applications in Genetics and Molecular Biology (2012)

Markov models provide a natural framework for modeling cellular and molecular level changes over time....

 

A Resampling-Based Approach to Multiple Testing with Uncertainty in Phase (with Victor G. DeGruttola), The International Journal of Biostatistics (2012)

Characterizing the genetic correlates to complex diseases requires consideration of a large number of potentially...

 

Multiple Imputation and Random Forests (MIRF) for Unobservable, High-Dimensional Data (with Bareng A. S. Nonyane), The International Journal of Biostatistics (2012)

Understanding the genetic underpinnings to complex diseases requires consideration of sophisticated analytical methods designed to...

 

Adult

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Prospective Studies

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

AIDS Serodiagnosis

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Child

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Anti-Retroviral Agents

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Longitudinal Data Analysis and Time Series

Ridge Regression for Longitudinal Biomarker Data (with Melissa Eliot, Jane Ferguson, and Muredach P. Reilly), The International Journal of Biostatistics (2012)

Technological advances facilitating the acquisition of large arrays of biomarker data have led to new...

 

Validation and Discovery in Markov Models of Genetics Data (with Victor De Gruttola), Statistical Applications in Genetics and Molecular Biology (2012)

Markov models provide a natural framework for modeling cellular and molecular level changes over time....

 

Computation

An Expectation Maximization Approach to Estimate Malaria Haplotype Frequencies in Multiply Infected Children (with Xiaohong Li, Recai M. Yucel, and Stephen M. Rich), Statistical Applications in Genetics and Molecular Biology (2012)

Characterizing genetic variability in the human pathogenic Plasmodium species, the group of parasites that cause...

 

HIV-1

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Genetics

Validation and Discovery in Markov Models of Genetics Data (with Victor De Gruttola), Statistical Applications in Genetics and Molecular Biology (2012)

Markov models provide a natural framework for modeling cellular and molecular level changes over time....

 

A Resampling-Based Approach to Multiple Testing with Uncertainty in Phase (with Victor G. DeGruttola), The International Journal of Biostatistics (2012)

Characterizing the genetic correlates to complex diseases requires consideration of a large number of potentially...

 

An Expectation Maximization Approach to Estimate Malaria Haplotype Frequencies in Multiply Infected Children (with Xiaohong Li, Recai M. Yucel, and Stephen M. Rich), Statistical Applications in Genetics and Molecular Biology (2012)

Characterizing genetic variability in the human pathogenic Plasmodium species, the group of parasites that cause...

 

Multiple Imputation and Random Forests (MIRF) for Unobservable, High-Dimensional Data (with Bareng A. S. Nonyane), The International Journal of Biostatistics (2012)

Understanding the genetic underpinnings to complex diseases requires consideration of sophisticated analytical methods designed to...

 

HIV Infections

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

Statistical Theory and Methods

A Resampling-Based Approach to Multiple Testing with Uncertainty in Phase (with Victor G. DeGruttola), The International Journal of Biostatistics (2012)

Characterizing the genetic correlates to complex diseases requires consideration of a large number of potentially...

 

Multiple Imputation and Random Forests (MIRF) for Unobservable, High-Dimensional Data (with Bareng A. S. Nonyane), The International Journal of Biostatistics (2012)

Understanding the genetic underpinnings to complex diseases requires consideration of sophisticated analytical methods designed to...

 

PDF

Metabolic and Anthropometric Parameters Contribute to ART-Mediated CD4+ T Cell Recovery in HIV-1-Infected Individuals: an Observational Study (with Livio Azzoni, Cynthia Firnhaber, Xiangfan Yin, Nigel J. Crowther, Deborah Glencross, Denise Lawrie, Wendy Stevens, Emmanouil Papasavvas, Ian Sanne, and Luis J. Montaner), Journal of the International AIDS Society (2011)

Background The degree of immune reconstitution achieved in response to suppressive ART is associated with...

 

Reproducibility of Results

PDF

Low-cost HIV-1 Diagnosis and Quantification in Dried Blood Spots by Real Time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Rongheng Lin, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)

BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...

 

No subject area

PDF

Ridge regression for longitudinal data with application to biomarkers (with Melissa N. Eliot, Muredach P. Reilly, and Jane Ferguson), Clinical and Translational Science Research Retreat (2011)

Introduction: Technological advances facilitating the acquisition of large arrays of biomarker data have led to...

 

Latent Variable Modeling Paradigms for Genotype-Traits Associated Studies, Biometrical Journal (2011)
 

Mixture Modeling as an Exploratory Framework for Genotype-Trait Associations, Journal of the Royal Statistical Society: Series C (2011)
 

PDF

Association between HIV replication and serum leptin levels: an observational study of a cohort of HIV-1-infected South African women (with Livio Azzoni, Nigel J. Crowther, and Cynthia Firnhaber), Journal of the International AIDS Society (2010)

Background - Advanced HIV infection can result in lipoatrophy and wasting, even in the absence...

 

PDF

Prediction-Based Classification for Longitudinal Biomarkers (with Livio Azzoni, Xiaohong Li, Margaret A. Johnson, Colette Smith, Karam Mounzer, and Luis J. Montaner), Annals of Applied Statistics (2010)

Assessment of circulating CD4 count change over time in HIV-infected subjects on antiretroviral therapy (ART)...

 

Applied Statistical Genetics with R (2009)
 

Estimating and Testing Haplotype-Trait Associations in Non-Diploid Populations (with X Li, B N. Thomas, S M. Rich, D Ecker, and JK Tumwine), Journal of the Royal Statistical Society: Series C (2009)

Malaria is an infectious disease that is caused by a group of parasites of the...

 

PDF

Tree-Based Methods for Discovery of Association between Flow Cytometry Data and Clinical Endpoints (with M. Eliot, L. Azzoni, C. Firnhaber, W. Stevens, D. K. Glencross, I. Sanne, and L. J. Montaner), Advances in Bioinformatics (2009)

We demonstrate the application and comparative interpretations of three tree-based algorithms for the analysis of...

 

PDF

Application of two machine learning algorithms to genetic association studies in the presence of covariates (with Bareng AS Nonyane), BMC Genetics (2008)

Background - Population-based investigations aimed at uncovering genotype-trait associations often involve high-dimensional genetic polymorphism data...

 

PDF

A Likelihood-Based Approach to Mixed Modeling with Ambiguity in Cluster Identifiers (with Recai Yucel and Xiaohong Li), Biostatistics (2008)

This manuscript describes a novel, linear mixed-effects model–fitting technique for the setting in which correlated...